Saturday's game between No. 24 Tulsa and the University of Houston has been postponed.
The American Athletic Conference announced late Tuesday that positive tests among Houston and contact tracing of student-athletes were behind the postponement.
The game may be rescheduled for Dec. 19 if neither team is a participant in the conference championship game.
It's the seventh time this season TU has had a game canceled or postponed because of COVID-19.
"Again, I'm disappointed for our student-athletes who have worked extremely hard in their preparations this fall, whether the game was played or not," said TU Director of Athletics Rick Dickson. "Our young men have continued to answer the bell to physically put themselves in the right spot to play each week. We wish the student-athletes and coaches at UH a speedy recovery."
TU games against Toledo and Northwestern State were canceled before the season opened. The OSU game was moved back a week to Sept. 19, while Arkansas State, Cincinnati, Navy and now Houston have been postponed as well.
Tulsa and Navy play Dec. 5 in Annapolis, Maryland. The Golden Hurricane will close out the regular season at H.A. Chapman Stadium against the No. 7 Cincinnati Bearcats on Dec. 12. Cincinnati is currently in first place in the American Athletic Conference.