The Oklahoma State Department of Health reported 169 new cases of COVID-19 on Friday, pushing the state's total to 5,849.
It was the state's largest single-day increase in cases in May and the most since 171 new cases on April 4.
Three new deaths were reported on Friday, with one each in Oklahoma, Tulsa and Texas counties. Two deaths were adults 65 or older, and one was a man between 50 and 64 years old.
COVID-19 has now killed 307 Oklahomans since March 18. It has hospitalized 926 people since it was first identified, and 190 people are currently hospitalized.
The health department reported 172 additional patients had recovered on Friday, bringing Oklahoma's total number of recoveries to 4,533. That leaves the state with 1,316 active COVID-19 cases.
Patients are considered to have recovered if they did not die, are not currently hospitalized and it has been at least 14 days since they tested positive. Symptoms of COVID-19 are known to linger for several weeks, however, in some cases.
According to the state, 152,998 tests have now been performed, giving the state a positive test rate of 3.8%. World Health Organization guidelines suggest positive test rates of less than 10% indicate adequate testing.