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Republicans digest a Friday apology from Sen. Trent Lott (R-MS) over remarks that seemed to endorse America's segregated past. Lott has declined to step down from his post as Senate Republican leader. Republicans must decide if he can remain effective. Hear from NPR's Jacki Lyden and NPR's Juan Williams.

NPR's Alex Chadwick talks with former Assistant Secretary of State Princeton Lyman about a letter he and 25 other former diplomats and military commanders have signed, calling for the defeat of George W. Bush in the November 2004 presidential election. In the letter, the group says Bush has so harmed international relations that only a new leader can repair them.

The request has renewed concerns about the Venezuelan president's health.

President Obama will also seek an emergency appropriation of more than $2 billion to deal with the surge of Central American immigrants flooding the southern border.

A veteran reporter's view on the hot-button issues in the coming year: Police in schools, the fallout from the Vergara case and more.

More than 200 migrants drowned on Sept. 21 trying to cross the Mediterranean to Europe, in search of better lives. A survivor explains why he risked the journey.

Governor Fallin issued a news release this afternoon to clarify her position on the state's A-F school grading system. In the news release, the Governor…

Sen. Hillary Clinton's impressive victory in Kentucky's Democratic primary does not change the math of the delegate race, which Sen. Barack Obama continues to lead. Clinton insists her big wins in Midwestern states make her a stronger candidate for the general election.

Rising prices are a top concern for voters in this year's midterm elections, outpacing abortion, crime and defending democracy. Prices in September were up 8.2% from a year ago.

Stephen Thompson looks at the biggest songs and albums of the week, and digs into the stories and trends beyond the Top 10.