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Americans for Prosperity first enlisted the Republican presidential candidate in 2005 to spearhead what it called the Prosperity Expansion Project. Herman Cain met his future campaign manager, his first press secretary and the architect of his 9-9-9 tax plan while working with the organization.

Pakistan has opened the door to billions of dollars worth of new trade with India. The decision might help reduce political and military tensions between the two rival nations.

The presidents of Afghanistan and Pakistan met in Istanbul Tuesday to discuss how to stabilize Afghanistan as foreign troops leave. A suicide attack in Kabul Saturday left 13 NATO forces dead, part of a string of recent violence. Host Renee Montagne speaks with Seth Jones of the RAND Corporation about the state of security.

A recent report by the research project found that one in three Americans raised in the middle class fall out of it as adults. Host Audie Cornish speaks with Erin Currier of the Pew Charitable Trusts' Economic Mobility Project about pressures on the American middle class.

Even though some popular heartburn medicines haven't been approved to treat babies, the medicines are being prescribed as a remedy for spitting up. Another option: modifying Mom's diet to make her breast milk more palatable.

TransCanada's proposed Keystone XL oil pipeline would cut through the Ogallala aquifer, a major water source that supplies about 80 percent of Nebraska's water for drinking and irrigation. Legislators have introduced bills preventing pipelines in environmentally sensitive areas.

The day's top news: Former Penn State coach charged with sexually abusing young boys; Iran said to be on "threshold of nuclear capability;" Greece prepares to form a new government.

In an emergency meeting on Saturday, the Arab League voted to suspend Syria, warning that the country could face sanctions if it does not end its brutal crackdown on protestors. Meanwhile, NATO leaders say a Libya-style military intervention is out of the question. NPR's Kelly McEvers reports on what other choices remain.

With the euro zone burdened by debt, the prime minister of Greece has resigned and Italy's long-time Premier Silvio Berlusconi is expected to step down as well. Guest host Linda Wertheimer checks in with NPR's Sylvia Poggioli, who sums up the events of a tumultuous week in Europe.

Philanthropist Evelyn Lauder died on Saturday. She co-founded the pink ribbon awareness movement to raise knowledge of breast health and cancer, and raised millions of dollars for cancer research.