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Serena Williams will not be playing for a grand slam Saturday in the women's singles final. She lost to Roberta Vinci in three sets in the U.S Open semifinal Friday.

The pandemic put infectious diseases doctors in the spotlight. The 'Fauci Effect' raised the number of fellowship applicants in 2020, but this year almost half of the training programs went unfilled.

NPR's Audie Cornish talks to Jon Wertheim of Sports Illustrated about the U.S. Open. Williams was ousted Monday after losing a close match, and Rafael Nadal was knocked off Sunday in a big upset.

Trump supporter and Jan. 6 protester Ray Epps sued Fox News over statements by former star Tucker Carlson that placed Epps at the center of the violent siege on the U.S. Capitol.

A gunman in southwest England killed five people, including a 3-year-old girl, before turning his weapon on himself, police say.

Also: Federal government is said have to warned Apple and publishers about alleged collusion on e-book pricing; world powers want "sustained dialogue" with Iran.

Also: Romney wins primary in Puerto Rico; fierce fighting erupts in Damascus; NCAA men's "sweet 16" field is set.

Also: Tuesday's strong earthquake in Mexico was "destructive but not deadly;" the Supreme Court and White House prepare for key health care cases; eastern Oklahoma braces for flooding.

News about the October unemployment rate leads the day's headlines.

While there are "murmurings" of a deal on deficit reduction, it's far from certain an agreement will be reached. Other news: Key witness in Penn State scandal says he did talk to university police; Syrian Army defectors reportedly attacked a base.