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Forty years ago, President Nixon signed the National Cancer Act, beginning the War on Cancer. Harold Varmus, director of the National Cancer Institute, discusses four decades of scientific progress in preventing, detecting and treating cancer--and the mysteries that still remain.

Some spend all year waiting for the holidays. But is excitement overrated? Author Ben Dolnick describes the emotional ups and downs of impatience.

NPR followed the 2nd Battalion, 8th Marine Regiment in 2009, on the homefront and in battle in Afghanistan. Daron Diepenbruck and Josh Apsey were members of that battalion and are now back home. One left the military; the other stayed in. Both say the war changed them.

Infant pain medicines are being changed to make them safer, but right now both old and new concentrations are on pharmacy shelves, increasing the risk of accidental overdoses that prompted the changes in the first place. Parents beware.

When a Mumbai hotel was besieged by terrorists in 2008, something extraordinary happened: Workers didn't flee. They stayed behind to help save guests at the risk of their own lives. What could possibly explain it? A new study attempts to answer that question.

Jessica Fellowes, author of a new book about the successful series Downton Abbey, talks about the story of the Crawleys and the world they inhabit.

Queen Elizabeth II's husband was hospitalized after experiencing chest pains.

A former Democrat turned Republican, he supports both the Tea Party and the Occupy Movement. The former Louisiana governor isn't going anywhere in the polls, but he is enjoying the ride.

The Justice Department has blocked a new South Carolina voting law, saying it violates the 1965 Voting Rights Act. The state law requires voters to present a photo ID in order to vote. The Justice Department says the law disenfranchises minorities, but the state says it protects against voter fraud. For more, Robert Siegel talks to NPR's Pam Fessler.

Jim Nayder, host of The Annoying Music Show! on Chicago Public Radio, returns with a fresh batch of truly irksome holiday music.