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Sen. Marco Rubio announced an end to his campaign following a loss in his home state of Florida to Donald Trump. Sitting Ohio Gov. John Kasich dealt Trump his only loss on Tuesday on his home turf.

People between 45 and 65 may be the loneliest segment in the U.S. And researchers are using brain scans to show that friendships are vital to staying healthy and engaged in your middle years.

In the local news:The state comes up $49 Million short just last month.Opposition is announced to the Vision Tax renewal.The founder of Tulsa's Quik-Trip…

Clinton won big; Trump continued his triumphant streak, with the notable exception of Kasich's win in Ohio; Rubio dropped out after a dismal showing in Florida. What that means, in five stories.

The goal is to rein in drug price increases while increasing the chance that patients will get the medication that works best for them. It's an idea that's getting increasing private-sector traction.

Gustavo Dudamel and members of the orchestra appeared in late night with inspiring music for a contentious campaign season.

Merrick Garland, a judge with 18 years' experience, was not the first choice of liberals. But President Obama hopes his ability to win over conservatives will extend to the Supreme Court.

What Washington, D.C., did — closing its Metrorail for 29 hours — sets it apart. Meanwhile, the developing world turns out to be developing some attractive transit options.

People often expect a great many things out of a marriage. That can work if spouses are pragmatic about what they're really able to deliver on, a study finds.

The bill would have created a national voluntary labeling standard — and prevented Vermont's mandatory labeling law from going into effect July 1. A compromise might yet be reached.