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Pakistan says it targeted militant hideouts along the Pakistan-Afghanistan border in response to militant attacks across Pakistan. Afghanistan condemned the strikes as acts of aggression.

U.S. and Iranian negotiators met separately on Wednesday with Qatari and Pakistani mediators, with "positive progress made," and they agreed to continue discussions, host Qatar said.

NPR's Ayesha Rascoe talks to Joan Kautz of Ironstone Vineyards, a winery in California, about the impact of Canadian tariffs on the U.S. alcohol industry.

We look at recent upheaval in Nepal, where Gen Z protesters toppled the government, and put the country's first female prime minister in power.

In this first glimpse of the "Sea Camp" series from NPR's Short Wave podcast, hear how climate change will significantly shift three-quarters of the ocean's surface currents by the end of the century.

Chileans head to the polls on Sunday, and an arch-conservative pledging mass migrant expulsions is strongly favored over his leftist opponent.

The Centers for Disease Control and Prevention will be facing a huge leadership vacuum, as Director Susan Monarez is forced out by RFK Jr. and the Trump administration.

NASA wants to land Artemis astronauts on the moon in 2027, but the scientific instruments they'll bring must be tested on Earth. The best place to do that is a mile-wide meteorite crater in Arizona.

NPR's Michel Martin speaks with Maine Secretary of State Shenna Bellows about her run to replace Graham Platner in the Maine Senate race.

Next week's primary in California includes a closely watched race between two Democrats in the state's Central Valley competing to unseat GOP Rep. David Valadao.