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Back in 1987, Nancy Cartwright made a risky, last-minute decision during an audition: Instead of trying out for the part of mild-mannered Lisa Simpson, she went for the role of rebellious Bart.

Hospitalizations in New York City, the original heart of the pandemic in early 2020, are growing exponentially because of omicron, and have now surpassed last winter's peak.

Employers from Macy's to United Airlines are having to adjust after skyrocketing omicron COVID cases have led large numbers of workers to call out sick.

The omicron wave in the U.S. will likely continue to the end of January, then start to recede rapidly. Former advisers to President Biden say a new strategy is needed to help the U.S. live with COVID.

NPR's Rachel Martin talks to Associated Press reporter Michael Balsamo about the wife of a jailed Mexican drug lord, who was arrested on charges of conspiracy to distribute drugs in the U.S.

In 2005, the British actor played brooding aristocrat Mr. Darcy in the film adaptation of Pride & Prejudice. Now, he's Tom Wambsgans, a scheming Midwesterner on the HBO series Succession.

Tropical Depression Grace is adding to the misery of the earthquake zone in Haiti, where doctors are scarce and efforts continue to find survivors of Saturday's quake.

After a video call with European allies, President Biden said there's unanimity on the threat posed by Russian troops on Ukraine's borders. Some allies are sending weapons to Ukraine. Others are not.

The Biden administration massively expanded hospital-level care at home as part of its strategy to enhance hospital capacity. The Mayo Clinic says it's having an impact.

Avah Lamie, 11, says this is a stressful time to be a kid. Rates of anxiety and depression among children and youth were on the rise even before COVID, but the past two years have made things worse.